Pharmaceutical preparations for prevention and/or treatment of antibody-mediated diseases, namely, systemic lupus erythematosus, RH hemolytic disease of the newborn, antiphospholipid antibody syndrome, Grave's disease, myasthenia gravis, Hashimoto's thyroiditis, pemphigus, autoimmune hemolytic anemia, autoimmune thrombocytopenia purpura, antibody mediated infertility, Sjogre's syndrome, mixed connective tissue disease, glomerulonephritis and Goodpasture's syndrome