Cell therapy reagents for use in vitro for medical use; biopharmaceuticals, namely, engineered protein arrays, polypeptides, and macromolecular complexes being protein arrays for use in vitro for medical use, namely, the treatment of cancer; biopharmaceuticals, namely, self-assembling protein-based nanoparticles for use in vitro for medical use, namely, the treatment of cancer; T-cell activator being reagents for use in vitro for medical use