Medical diagnostic assays for testing for the presence of biomarkers in uterine tissue for determining a patient's personalized treatment plan; medical diagnostic assays for testing for the presence normal lactobacillus and targeted pathogenic bacteria, namely Escherichia, Klebsiella, Enterococcus, Streptococcus, Mycoplasma, Chlamydia, Ureaplasma, Neisseria, Staphylococcus, and Gardnerella.

Medical diagnostic assays for testing for the presence of biomarkers in uterine and vaginal tissue for determining a patient's personalized treatment plan; medical diagnostic assays for testing of uterine and vaginal tissue for bacterial, fungal and resistance markers for determining a personalized treatment plan.