medical and surgical apparatus, including but not limited to implantable prostheses, endsoscopic accessories, laparoscopic accessories, valvuloplasty devices, gastrointenstinal accessories, endoluminal therapies, tissue approximation and attachment devices, endomill suturing system and endomill suturing device, tissue graspers and manipulators, medical monitoring or sensing devices, nanotechnology sensing and delivery devices, pharmacological delivery mechanisms, and the like