Describing and providing medical diagnostic and pharmaceutical preparations with nucleotide sequences that have a low content of, or fully lack, adenosine, for testing, preventing, and therapeutically treating human and non-human animal respiratory ailments that may be associated with hyper-sensitivity or hyper-responsiveness to adenosine, including bronchoconstriction, difficult breathing, impeded and obstructed lung airways, allergy(ies) and/or inflammation, which in many cases are adenosin...